Invisible Enemies: Stories of Infectious Disease by Jeanette Farrell. This nonfiction book for young adults (272 pages) covers smallpox, leprosy, plague, tuberculosis, malaria, cholera, and AIDS.
Outbreak! Plagues That Changed Historyby Bryn Barnard. Another nonfiction treatment that relates historical changes to epidemic outbreaks, this book has chapters on plague, smallpox, yellow fever, cholera, tuberculosis, and influenza.
A House of Tailors by Patricia Reilly Giff. In 1870, 13 year old Dina emigrates from Germany to Brooklyn and finds herself in the midst of a smallpox epidemic.
Blue by Joyce Moyer Hostetter. Anna Fay’s little brother Bobby falls victim to the polio pandemic in 1944 even as their father is fighting the Germans in Europe.
Close to Home: A Story of the Polio Epidemic by Lydia Weaver.
A Doctor Like Papa by Natalie Kinsey-Warnock. Eleven year old Margaret wants to be a doctor like her father when she grows up, her mother says that doctoring isn’t a job for girls.
Hero Over Here by Kathleen Kudlinski. Theodore’s father and brothers are heroes —fighting the enemy during World War I. Theo learns his own lesson about heroism when he must take care of his entire family, mother and sisters, during the deadly flu epidemic of 1918.
A Time of Angels by Karen Hesse. Hannah flees Boston to escape the 1918 Spanish flu epidemic, but she must battle both influenza and prejudice in Battleboro, Vermont where she makes a new life for herself.
Listening for Lions by Gloria Whelan. When Rachel’s missionary parents die in an influenza epidemic in 1919 in Kenya, she is sent by scheming neighbors to England to pose as their daughter for a rich grandfather who may leave his estate to his fake granddaughter if she can endear herself to him.
The Boy Who Saved Cleveland by James Cross Giblin. In 1798, Cleveland is just a small village, and when malaria strikes the families settled there, ten year old Seth is their only hope of survival.
Graveyard Girl by Anna Myers. Grace is the Graveyard Girl who must toll the bell each day for all those who have died of yellow fever in Memphis, 1878, and her friend Eli must learn to move past his grief over the deaths of his mother and younger sister.
A Parcel of Patterns by Jill Paton Walsh. A village is quarantined, no one allowed in or out, in seventeenth century England, when the plague infects the villagers by means of an innocent-looking parcel sent from London.
Master Cornhill by Eloise Jarvis McGraw. A 11 year old orphan boy survives in London during the Great Fire and the Black Plague.
Any more suggestions?